2. Protein Tyrosine Kinase/RTK
  3. FLT3
  4. HP1328

HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia.

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HP1328 Chemical Structure

HP1328 Chemical Structure

CAS No. : 2245074-20-6

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HP1328 Related Antibodies

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Description

HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia[1].

Molecular Weight

389.45

Formula

C23H23N3O3
CAS No.
SMILES

OCCOC1=CC=C(CNC2=CC(N=CN3C4=CC=CC=C4)=C3C=C2)C=C1OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HP1328 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HP13282245074-20-6HP 1328HP-1328FLT3Cluster of differentiation antigen 135CD135Fms like tyrosine kinase 3tyrosine kinasebenzoimidazolescaffold-basedleukemiaInhibitorinhibitorinhibit

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