2. Metabolic Enzyme/Protease
  3. Amylases Glucosidase
  4. HPA-IN-1

HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively.

For research use only. We do not sell to patients.

HPA-IN-1 Chemical Structure

HPA-IN-1 Chemical Structure

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HPA-IN-1 Related Antibodies

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Description

HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively[1].

IC50 & Target

IC50: 12.0 μM (HPA), 410.4 μM (α-glucosidase)[1]
In Vitro

HPA-IN-1 (Compound 1) has three hydrogen bonds interacting with HPA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HPA-IN-1 Related Antibodies
Molecular Weight

660.63

Formula

C33H32N4O11
SMILES

O=C(NCC1=CN(N=N1)CCCCCCOC2=C(OC3=C(C=C(C=C3C2=O)O)O)C4=CC(O)=C(C(O)=C4)O)/C=C/C5=CC=C(C(O)=C5)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPA-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPA-IN-1AmylasesGlucosidasehuman pancreatic α-amylaseHPAα-glucosidaseanti-diabetes mellitusInhibitorinhibitorinhibit

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HPA-IN-1
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HY-143268
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