HPK1-IN-9

Cat. No.: HY-145035: FAQs
Data Sheet Handling Instructions

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HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) .

For research use only. We do not sell to patients.

HPK1-IN-9 Chemical Structure

CAS No. : 2734168-78-4

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Description	HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) ^[1].
Molecular Weight	523.63
Formula	C₃₀H₃₃N₇O₂
CAS No.	2734168-78-4
SMILES	O=C(N1CC(C1)N(C)C)C2=CC=C(C3=CNC4=C3N=C(C5=CC=C6C(OCC7N6CCN(C7)C)=C5)C=N4)C=C2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.

HPK1-IN-9 Related Classifications

Molarity Calculator
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-92734168-78-4MAP4KMAPK Kinase Kinase KinaseHPK1hematopoietic progenitor cellSte-20-related protein kinasesInhibitorinhibitorinhibit

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HPK1-IN-9

HPK1-IN-9 Related Antibodies

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