2. Metabolic Enzyme/Protease
  3. 17β-HSD
  4. HSD17B13-IN-27

HSD17B13-IN-27 (compound 30) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of ＜ 0.1 μM and ?＜ 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-27? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis).

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HSD17B13-IN-27 Chemical Structure

HSD17B13-IN-27 Chemical Structure

CAS No. : 2758802-31-0

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HSD17B13-IN-27 Related Antibodies

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Description

HSD17B13-IN-27 (compound 30) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of ＜ 0.1 μM and ?＜ 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-27? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].

Molecular Weight

414.45

Formula

C21H19FN2O4S
CAS No.
SMILES

FC1=C(O)C=CC(C(NC2=C(C(NCCC3=C(OC)C=CC=C3)=O)SC=C2)=O)=C1
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Purity & Documentation
References
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HSD17B13-IN-27 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HSD17B13-IN-272758802-31-017β-HSD17beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenasenonalcoholic fatty liver diseases (NAFLDs),? NASH (nonalcoholic steatohepatitis)Inhibitorinhibitorinhibit

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