2. Metabolic Enzyme/Protease
  3. 17β-HSD
  4. HSD17B13-IN-83

HSD17B13-IN-83 (Compound 150) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-83 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI).

For research use only. We do not sell to patients.

HSD17B13-IN-83 Chemical Structure

HSD17B13-IN-83 Chemical Structure

CAS No. : 2770247-41-9

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HSD17B13-IN-83 Related Antibodies

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Description

HSD17B13-IN-83 (Compound 150) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-83 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].

Molecular Weight

557.28

Formula

C23H14Cl2F4N4O4
CAS No.
SMILES

O=C(C1=NC(Cl)=C(C(Cl)=C1)O)NC2=CC=C(C(N=C(C)N3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HSD17B13-IN-83 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HSD17B13-IN-832770247-41-917β-HSD17beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenaseNAFLDNASHdrug-induced liver injury (DILI)Inhibitorinhibitorinhibit

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