Hydromethylthionine dihydrobromide (Synonyms: Leukomethylene blue dihydrobromide; LMTM dihydrobromide)

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Hydromethylthionine dihydrobromide (Leukomethylene blue dihydrobromide) is a potent inhibitor of TAU protein aggregation. Hydromethylthionine dihydrobromide reduces neurodegeneration by interacting with TAU proteins and preventing them from forming neurotoxic aggregates. Hydromethylthionine dihydrobromide can be used in the study of Alzheimer's disease and other TAU related disorders.

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Hydromethylthionine dihydrobromide Chemical Structure

CAS No. : 951131-15-0

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Other In-stock Forms of Hydromethylthionine dihydrobromide:

Leucomethylene blue mesylate

Other Forms of Hydromethylthionine dihydrobromide:

Leucomethylene blue mesylate In-stock
Hydromethylthionine Get quote

6 Publications Citing Use of MCE Hydromethylthionine dihydrobromide

: Hydromethylthionine dihydrobromide purchased from MedChemExpress. Usage Cited in: Bioorg Med Chem. 2018 Sep 1;26(16):4693-4705. [Abstract]; Imaging of HEK-293T cells incubated with or without LMTM (0.5 μM) and 30 (1 μM).

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Description	Hydromethylthionine dihydrobromide (Leukomethylene blue dihydrobromide) is a potent inhibitor of TAU protein aggregation. Hydromethylthionine dihydrobromide reduces neurodegeneration by interacting with TAU proteins and preventing them from forming neurotoxic aggregates. Hydromethylthionine dihydrobromide can be used in the study of Alzheimer's disease and other TAU related disorders^[1].
Molecular Weight	447.23
Formula	C₁₆H₂₁Br₂N₃S
CAS No.	951131-15-0
SMILES	CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1.Br.Br
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Kondak C, et al. Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine[J]. Journal of neurochemistry, 2022, 160(2): 172-184. [Content Brief]

Hydromethylthionine dihydrobromide Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydromethylthionine dihydrobromide951131-15-0Leukomethylene blue dihydrobromideLMTM dihydrobromideTau ProteinAggregation inhibitorTAUNeurotoxicityAlzheimer's diseaseInhibitorinhibitorinhibit

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Hydromethylthionine dihydrobromide (Synonyms: Leukomethylene blue dihydrobromide; LMTM dihydrobromide)

Other Forms of Hydromethylthionine dihydrobromide:

Hydromethylthionine dihydrobromide Related Antibodies

6 Publications Citing Use of MCE Hydromethylthionine dihydrobromide

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Hydromethylthionine dihydrobromide Related Classifications

Molarity Calculator

Dilution Calculator