1. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Isotope-Labeled Compounds Histamine Receptor
  3. Hydroxyzine-d8 dihydrochloride

Hydroxyzine-d8 (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

For research use only. We do not sell to patients.

Hydroxyzine-d<sub>8</sub> dihydrochloride Chemical Structure

Hydroxyzine-d8 dihydrochloride Chemical Structure

CAS No. : 1808202-93-8

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Description

Hydroxyzine-d8 (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

IC50 & Target

H1 Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

455.88

Formula

C21H21D8Cl3N2O2

CAS No.
Unlabeled CAS

2192-20-3

SMILES

OCCOCCN(C([2H])([2H])C1([2H])[2H])C([2H])([2H])C([2H])([2H])N1C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Hydroxyzine-d8 dihydrochloride
Cat. No.:
HY-B0548AS2
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