1. Stem Cell/Wnt
  2. β-catenin
  3. I-67

I-67, a structural isomer of I-66 (HY-P10925), is a potent β-catenin inhibitor with an IC50 of <50 nM. I-67 can inhibits β-catenin and T-cell factor (TCF) transcription factor interaction. I-67 shows anticancer effects.

For research use only. We do not sell to patients.

I-67 Chemical Structure

I-67 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of I-67:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

I-67, a structural isomer of I-66 (HY-P10925), is a potent β-catenin inhibitor with an IC50 of <50 nM. I-67 can inhibits β-catenin and T-cell factor (TCF) transcription factor interaction. I-67 shows anticancer effects[1].

Molecular Weight

2076.39

Formula

C102H134N18O25S2

Sequence

c-PL3-Asp-Npg-B5-Asp-3COOHF-Aib-Ala-Phe-Lys*3-PyrS2-3Thi-BztA-GlnR*3-Ala-NH2

SMILES

OC(C1=CC(C[C@@H](C(NC(C)(C)C(N[C@@H](C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@]3(CN(C(OCCC/C=C\CCC[C@@]4(CCC/C=C\C[C@]5(CCCN5C(C)=O)C6=O)NC([C@H](CC(C)(C)C)NC([C@H](CC(O)=O)N6)=O)=O)=O)CC3)C7=O)=O)CCCCNC(CC[C@@H](C(N[C@@H](C)C(N)=O)=O)NC([C@H](CC8=CSC9=C8C=CC=C9)NC([C@H](CC%10=CSC=C%10)N7)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC4=O)=O)=CC=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

I-67 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
I-67
Cat. No.:
HY-P10925A
Quantity:
MCE Japan Authorized Agent: