2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. IAA65

IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 µM. IAA65 can be used for epilepsy research.

For research use only. We do not sell to patients.

IAA65 Chemical Structure

IAA65 Chemical Structure

CAS No. : 2987139-96-6

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IAA65 Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 µM. IAA65 can be used for epilepsy research[1].

IC50 & Target

T-type calcium channel

 

In Vitro

IAA65 (50 µM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation[1].
IAA65 (50 µM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

IAA65 Related Antibodies
Molecular Weight

365.27

Formula

C16H13F6NO2
CAS No.
SMILES

O=C(NC1=CC(CC(C)C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IAA65 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IAA652987139-96-6IAA 65IAA-65Calcium ChannelCa2+ channelsCa channelsT-type calcium channelepilepsyInhibitorinhibitorinhibit

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