IHR-Cy3

Cat. No.: HY-131016: FAQs
Data Sheet Handling Instructions

Molarity Calculator

IHR-Cy3 is a potent fluorescent Smo antagonist with an IC₅₀ of 100 nM.

For research use only. We do not sell to patients.

IHR-Cy3 Chemical Structure

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

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Description	IHR-Cy3 is a potent fluorescent Smo antagonist with an IC₅₀ of 100 nM^[1].
IC₅₀ & Target	IC50: 100 nM^[1]
Molecular Weight	1174.64
Formula	C₅₈H₆₃Cl₃N₆O₁₀S₂
SMILES	ClC1=CC=C(C(C(NC2=CC=C(C=C2)NC(C3=C(C=CC(NC(CCCCCCNC(CCCCC[N+]4=C(C(C)(C5=C4C=CC(S(=O)(O)=O)=C5)C)/C=C/C=C6N(C7=C(C/6(C)C)C=C(S(=O)([O-])=O)C=C7)CC)=O)=O)=C3)Cl)=O)=O)=C1)Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Chih-Wei Fan, et al. The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation. Chem Biol [Content Brief]

IHR-Cy3 Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IHR-Cy3SmoSmoothenedAntagonistfluorescentInhibitorinhibitorinhibit

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IHR-Cy3

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