Immethridine dihydrobromide

Cat. No.: HY-108058A: Data Sheet Handling Instructions Technical Support

Immethridine dihydrobromide is a selective histamine H3 receptor (H3R) agonist. Immethridine dihydrobromide displays 300-fold selectivity over the H4 receptor and does not bind to H1 or H2 receptors. Immethridine dihydrobromide can be used for experimental autoimmune encephalomyelitis (EAE) research.

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Immethridine dihydrobromide Chemical Structure

CAS No. : 699020-93-4

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Description	Immethridine dihydrobromide is a selective histamine H3 receptor (H3R) agonist. Immethridine dihydrobromide displays 300-fold selectivity over the H4 receptor and does not bind to H1 or H2 receptors. Immethridine dihydrobromide can be used for experimental autoimmune encephalomyelitis (EAE) research^[1].
Molecular Weight	321.01
Formula	C₉H₁₁Br₂N₃
CAS No.	699020-93-4
SMILES	[H]Br.[H]Br.C1(CC2=CN=CN2)=CC=NC=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Shi Y, et al. Immethridine, histamine H3-receptor (H3R) agonist, alleviated experimental autoimmune encephalomyelitis via inhibiting the function of dendritic cells. Oncotarget. 2017 Aug 24;8(43):75038-75049. [Content Brief]