2. Induced Disease Models Products
  3. Immunology and Inflammatory Disease Models
  4. Gastrointestinal Inflammation and Ulcer Models
  5. Inflammatory Bowel Disease (IBD) Models

Inflammatory Bowel Disease (IBD) Models

Inflammatory Bowel Disease (IBD) Models (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126360
    Oxazolone 15646-46-5 ≥98.0%
    Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins.
    Oxazolone
  • HY-116282C
    Dextran sulfate sodium salt (MW 35000-50000) 9011-18-1
    Dextran sulfate sodium salt (MW 35000-50000) is a polymer of anhydroglucose and is a potent inducer of colitis. Dextran sulfate sodium salt (MW 35000-50000) may be related to macrophage dysfunction, intestinal flora dysbiosis, and is particularly toxic to the colonic epithelium. Dextran sulfate sodium salt (MW 35000-50000) also inhibits human immunodeficiency virus replication by preventing viral adsorption to host cells. Dextran sulfate sodium salt (MW 35000-50000) is also used to bind to insulin, encapsulate it in gold nanoparticles, and serve as an insulin carrier to bind to insulin receptors to achieve the purpose of slowly releasing insulin and prolonging insulin activity.
    Dextran sulfate sodium salt (MW 35000-50000)