InteriotherinA

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Interiotherin A is a lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura interior. Interiotherin A inhibits HIV replication to exhibit anti-HIV activity, it has a role as a metabolite and an anti-HIV agent.

For research use only. We do not sell to patients.

InteriotherinA Chemical Structure

CAS No. : 181701-06-4

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HIV HIV-1 HIV-2

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Description

In Vitro

Interiotherin A (Compounds 1) (0.8-100μg/mL; 4 hours) inhibits HIV replication with EC₅₀ values of 3.1 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:	T cell line: HS1
Concentration:	100 µg/mL, 20 µg/mL, 4 µg/mL, and 0.8 µg/mL
Incubation Time:	4 hours
Result:	Exhibited anti-HIV activity.

Molecular Weight

504.53

Formula

C₂₉H₂₈O₈

CAS No.

181701-06-4

SMILES

COC1=C2C3=C(CC(C)C(C)C(OC(C4=CC=CC=C4)=O)C2=CC5=C1OCO5)C=C(OCO6)C6=C3OC

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chen DF, et al. Two new lignans, interiotherins A and B, as anti-HIV principles from Kadsura interior. J Nat Prod. 1996 Nov;59(11):1066-8. [Content Brief]

InteriotherinA Related Classifications

Metabolic Disease Infection

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

InteriotherinA181701-06-4HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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