2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. IONIS PTP1BRx

IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity.

For research use only. We do not sell to patients.

DNA, d(P-thio)([2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]rG-T-T-T-A-T-T-m5C-m5C-A-T-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA)

IONIS PTP1BRx Chemical Structure

CAS No. : 1403406-29-0

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IONIS PTP1BRx Related Antibodies

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Description

IONIS PTP1BRx (ISIS 404173) is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B). IONIS PTP1BRx shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity[1].

CAS No.
SMILES

[IONIS PTP1BRx]
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Purity & Documentation
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IONIS PTP1BRx Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IONIS PTP1BRx1403406-29-0ISIS 404173ISIS404173ISIS-404173PhosphatasePTP-1B inhibitorantisenseantidiabetic activitytype 2 diabetesInhibitorinhibitorinhibit

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