Ipsapirone hydrochloride  (Synonyms: TVX Q 7821)

Ipsapirone hydrochloride (TVX Q 7821) is an anxiolytic compound and a 5-HT_1A receptor partial agonist. Ipsapirone hydrochloride (TVX Q 7821) also exhibits 5-HT_1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT₂ and the α₁-adrenergic function^[1][2].

437.94

C₁₉H₂₄ClN₅O₃S

92589-98-5

O=C(C1=C2C=CC=C1)N(CCCCN3CCN(C4=NC=CC=N4)CC3)S2(=O)=O.Cl

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. J Maj, et al. Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions. J Neural Transm. 1987;70(1-2):1-17.  [Content Brief]

  [2]. Stephen M. Stahl, et al. Effectiveness of ipsapirone, a 5-HT-1A partial agonist, in major depressive disorder: support for the role of 5-HT-1A receptors in the mechanism of action of serotonergic antidepressants. Int J Neuropsychopharmacol. 1998 Jul;1(1):11-18.  [Content Brief]