2. Others Apoptosis
  3. Fluorescent Dye Apoptosis
  4. IR-783

IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer.

For research use only. We do not sell to patients.

IR-783 Chemical Structure

IR-783 Chemical Structure

CAS No. : 115970-66-6

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
10 mg USD 25 In-stock
50 mg USD 50 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

IR-783 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer[1].

Molecular Weight

749.35

Formula

C38H46ClN2NaO6S2
CAS No.
Appearance

Solid

Color

Green to dark green

SMILES

O=[S](CCCCN(/C1=C\C=C(CCC2)\C(Cl)=C2/C=C/C(C3(C)C)=[N+](C4=CC=CC=C34)CCCC[S](=O)([O-])=O)C5=CC=CC=C5C1(C)C)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 116.67 mg/mL (155.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3345 mL 6.6725 mL 13.3449 mL
5 mM 0.2669 mL 1.3345 mL 2.6690 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.87%

COA (260 KB) HNMR (139 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3345 mL 6.6724 mL 13.3449 mL 33.3622 mL
5 mM 0.2669 mL 1.3345 mL 2.6690 mL 6.6724 mL
10 mM 0.1334 mL 0.6672 mL 1.3345 mL 3.3362 mL
15 mM 0.0890 mL 0.4448 mL 0.8897 mL 2.2241 mL
20 mM 0.0667 mL 0.3336 mL 0.6672 mL 1.6681 mL
25 mM 0.0534 mL 0.2669 mL 0.5338 mL 1.3345 mL
30 mM 0.0445 mL 0.2224 mL 0.4448 mL 1.1121 mL
40 mM 0.0334 mL 0.1668 mL 0.3336 mL 0.8341 mL
50 mM 0.0267 mL 0.1334 mL 0.2669 mL 0.6672 mL
60 mM 0.0222 mL 0.1112 mL 0.2224 mL 0.5560 mL
80 mM 0.0167 mL 0.0834 mL 0.1668 mL 0.4170 mL
100 mM 0.0133 mL 0.0667 mL 0.1334 mL 0.3336 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

IR-783 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IR-783115970-66-6ADS 780WSIR783IR 783Fluorescent DyeApoptosisFluorescence ProbeMDA-MB-231 xenograft modelbreast cancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
IR-783
Cat. No.:
HY-139109
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.