2. Cell Cycle/DNA Damage
  3. IRE1
  4. IRE1α kinase-IN-5

IRE1α kinase-IN-5 (compound 7) is a potent IRE1α inhibitor with an Ki of 98 nM. IRE1α kinase-IN-5 is the ATP-competitive ligands of IRE1α.

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IRE1α kinase-IN-5 Chemical Structure

IRE1α kinase-IN-5 Chemical Structure

CAS No. : 2771006-47-2

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IRE1α kinase-IN-5 Related Antibodies

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Description

IRE1α kinase-IN-5 (compound 7) is a potent IRE1α inhibitor with an Ki of 98 nM. IRE1α kinase-IN-5 is the ATP-competitive ligands of IRE1α[1].

IC50 & Target

Ki: 98 nM (IRE1α)[1]
Molecular Weight

530.64

Formula

C28H30N6O3S
CAS No.
SMILES

O=S(NC(C1=C2C=CC=C1)=CC=C2OC3=NC=CC=C3C4=NC(N[C@H]5CC[C@H](N)CC5)=NC=C4)(C6CC6)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IRE1α kinase-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IRE1α kinase-IN-52771006-47-2IRE1Inositol requiring enzyme 1ATP-competitive ligandsINS-1 cellsendoplasmic reticulumunfolded protein responseInhibitorinhibitorinhibit

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IRE1α kinase-IN-5
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