2. Immunology/Inflammation
  3. STING
  4. ISD sodium

ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis.

For research use only. We do not sell to patients.

DNA, (5'-TACAGATCTACTAGTGATCTATGACTGATCTGTACATGATCTACA-3'), complex with DNA, (3'-ATGTCTAGATGATCACTAGATACTGACTAGACATGTACTAGATGT-5'), sodium salt

ISD sodium Chemical Structure

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10 mg USD 800 In-stock
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Based on 1 publication(s) in Google Scholar

ISD sodium Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE ISD sodium

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  • Purity & Documentation

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Description

ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis[1].

Appearance

Solid

Color

White to off-white

SMILES

[ISD (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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ISD sodium Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ISDSTINGStimulator of Interferon GenesTMEM173MITAERISMPYSnon-CpG oligomerIFN-βSTING-TBK1-IRF3Inhibitorinhibitorinhibit

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ISD sodium
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HY-160225
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