2. Natural Products
  3. Plants Disease Research Fields Terpenoids
  4. Leguminosae Inflammation/Immunology Compositae Sesquiterpenes
  5. Amorpha fruticosaL.
  6. Isoscabertopin

Isoscabertopin is a sesquiterpene lactone isolated from Elephantopus scaber L and shows anti-tumor activities.

For research use only. We do not sell to patients.

Isoscabertopin Chemical Structure

Isoscabertopin Chemical Structure

CAS No. : 439923-16-7

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Based on 1 publication(s) in Google Scholar

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Description

Isoscabertopin is a sesquiterpene lactone isolated from Elephantopus scaber L and shows anti-tumor activities[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: Scabertopin
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 35090346]
NCI-H460 IC50
> 10 μM
Compound: Scabertopin
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 35090346]
Molecular Weight

358.39

Formula

C20H22O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C/C=C(C)\C(O[C@@H](CC1=C2)[C@]3([H])[C@@](OC(C3=C)=O)([H])/C=C(C)/C[C@@]2([H])OC1=O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Purity: ≥99.0%

SDS (251 KB)

COA (265 KB)

Handling Instructions (2659 KB)
References
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Isoscabertopin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoscabertopin439923-16-7OthersElephantopus scaber Lanti-tumorapoptosisInhibitorinhibitorinhibit

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