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  5. Eupatorium buniifolium Hook. & Arn.
  6. Isotanshinone II

Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease.

For research use only. We do not sell to patients.

Isotanshinone II Chemical Structure

Isotanshinone II Chemical Structure

CAS No. : 98249-39-9

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Isotanshinone II Related Antibodies

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Description

Isotanshinone II is a natural product that can be isolated from Salvia glutinos. Isotanshinone II can be used to study Alzheimer's disease[1].

Cellular Effect
Cell Line Type Value Description References
AGS IC50
> 20 μM
Compound: 12, isotanshinone ii
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
AGS IC50
> 50 μM
Compound: 12, isotanshinone ii
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
Hep 3B2 IC50
> 20 μM
Compound: 12, isotanshinone ii
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
Hep 3B2 IC50
> 50 μM
Compound: 12, isotanshinone ii
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
Molecular Weight

276.29

Formula

C18H12O3
CAS No.
SMILES

O=C(C1=C(C2=C3C=CC4=C2C=CC=C4C)OC=C1C)C3=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Isotanshinone II Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isotanshinone II98249-39-9OthersNatural ProductAlzheimer's diseaseInhibitorinhibitorinhibit

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