2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling Cell Cycle/DNA Damage
  3. JAK HDAC
  4. JAK/HDAC-IN-3

JAK/HDAC-IN-3 (13a) is a dual JAK and HDAC inhibitor, with IC50 values of 25.36 nM, 0.2 μM and 0.43 μM for JAK2, HDAC and HDAC1, respectively.

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JAK/HDAC-IN-3 Chemical Structure

JAK/HDAC-IN-3 Chemical Structure

CAS No. : 3029138-70-0

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JAK/HDAC-IN-3 Related Antibodies

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JAK1 JAK2 JAK3 Tyk2 JAK

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

JAK/HDAC-IN-3 (13a) is a dual JAK and HDAC inhibitor, with IC50 values of 25.36 nM, 0.2 μM and 0.43 μM for JAK2, HDAC and HDAC1, respectively[1].

Molecular Weight

588.69

Formula

C28H37FN6O5S
CAS No.
SMILES

CC(NS(C1=CC(NC2=NC(NC3=CC=C(C(F)=C3)OCCCCCCC(NO)=O)=NC=C2C)=CC=C1)(=O)=O)(C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JAK/HDAC-IN-3 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JAK/HDAC-IN-33029138-70-0JAKHDACJanus kinaseHistone deacetylasesHDAC1JAK2Inhibitorinhibitorinhibit

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