2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. JAK-IN-30

JAK-IN-30 (compound 31) is a water-soluble JAK inhibitor with IC50 values of 2, 15, 18 and 2 nM for JAK2, JAK1, JAK3 and TYK2, respectively. JAK-IN-30 has research potential for dry eye disease (DED).

For research use only. We do not sell to patients.

JAK-IN-30 Chemical Structure

JAK-IN-30 Chemical Structure

CAS No. : 2891469-99-9

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JAK-IN-30 Related Antibodies

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JAK1 JAK2 JAK3 Tyk2 JAK

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Description

JAK-IN-30 (compound 31) is a water-soluble JAK inhibitor with IC50 values of 2, 15, 18 and 2 nM for JAK2, JAK1, JAK3 and TYK2, respectively. JAK-IN-30 has research potential for dry eye disease (DED)[1].

IC50 & Target[1]

JAK1

15 nM (IC50)

JAK2

2 nM (IC50)

JAK3

18 nM (IC50)

Tyk2

2 nM (IC50)

Molecular Weight

398.53

Formula

C19H26N8S
CAS No.
SMILES

N#CCC1(N2CCN(CC2)C)CN(C1)C(N=C3NC4=CC(C)=NS4)=C(C=N3)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JAK-IN-30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JAK-IN-302891469-99-9JAKJanus kinaseA549HBL-100HeLaSW1573T-47DWiDcancerapoptosisInhibitorinhibitorinhibit

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