2. GPCR/G Protein
  3. Vasopressin Receptor
  4. JKC 301

JKC 301 is a selective Endothelin A receptor antagonist. JKC 301 attenuates the pressor effects of nicotine in rats. JKC 301 can be used to study cardiovascular disease caused by smoking.

For research use only. We do not sell to patients.

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JKC 301 Chemical Structure

JKC 301 Chemical Structure

CAS No. : 136553-96-3

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JKC 301 Related Antibodies

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Description

JKC 301 is a selective Endothelin A receptor antagonist. JKC 301 attenuates the pressor effects of nicotine in rats. JKC 301 can be used to study cardiovascular disease caused by smoking[1][2].

IC50 & Target

Endothelin A receptor[1][2].
Molecular Weight

624.73

Formula

C32H44N6O7
CAS No.
Sequence

Cyclo({d-Asp}-Pro-{d-Ile}-Leu-{d-Trp})
Sequence Shortening

Cyclo({d-Asp}-P-{d-Ile}-L-{d-Trp})
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JKC 301 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JKC 301136553-96-3JKC301JKC-301Vasopressin Receptorsmokenicotinecardiovascular diseaseInhibitorinhibitorinhibit

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