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  3. JNJ19567470

JNJ19567470  (Synonyms: R317573; CRA5626; TAI041)

Cat. No.: HY-107095
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JNJ19567470 (R317573) is a selective, non-peptidergic CRF type 1 receptor (CRF1) antagonist. JNJ19567470 blocks NaLac-induced panic-like behaviour and cardiovascular responses. JNJ19567470 decreases regional glucose utilization in the amygdala, and attenuates anxiety responses.

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JNJ19567470 Chemical Structure

JNJ19567470 Chemical Structure

CAS No. : 724471-26-5

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Description

JNJ19567470 (R317573) is a selective, non-peptidergic CRF type 1 receptor (CRF1) antagonist. JNJ19567470 blocks NaLac-induced panic-like behaviour and cardiovascular responses. JNJ19567470 decreases regional glucose utilization in the amygdala, and attenuates anxiety responses[1][2].

Molecular Weight

443.38

Formula

C22H27BrN4O

CAS No.
SMILES

BrC1=CC(C)=C(N2C=C(C)C3=C(N4CCC(CC4)CO)N=C(C)N=C32)C(C)=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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JNJ19567470 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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JNJ19567470
Cat. No.:
HY-107095
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