2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. JTP-117968

JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation.

For research use only. We do not sell to patients.

JTP-117968 Chemical Structure

JTP-117968 Chemical Structure

CAS No. : 2250132-99-9

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JTP-117968 Related Antibodies

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Description

JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].

In Vitro

JTP-117968 has partial TR activity, but exhibits extremely low TA activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

JTP-117968 Related Antibodies
Molecular Weight

520.59

Formula

C31H31F3N2O2
CAS No.
SMILES

O=C(C(C=C1C2)=CC=C1[C@]3(CC4=CC=CC=C4)CC[C@@](C(F)(F)F)(O)C[C@@]3([H])C52CC5)NC6=CC=CN=C6C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JTP-117968 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JTP-1179682250132-99-9JTP117968JTP 117968Glucocorticoid Receptorglucocorticoid receptorSGRMtransrepressiontransactivationA549lung cancerNSCLCInhibitorinhibitorinhibit

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JTP-117968
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HY-125265
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