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  4. JTV-519 fumarate

JTV-519 fumarate (K201 fumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. JTV-519 fumarate is a cardioprotective agent with antiarrhythmic effects.

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JTV-519 fumarate Chemical Structure

JTV-519 fumarate Chemical Structure

CAS No. : 1883549-36-7

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JTV-519 fumarate Related Antibodies

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Description

JTV-519 fumarate (K201 fumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. JTV-519 fumarate is a cardioprotective agent with antiarrhythmic effects[1][2].

IC50 & Target

SERCA[1]
Molecular Weight

540.67

Formula

C29H36N2O6S
CAS No.
SMILES

COC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1.O=C(O)/C=C/C(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JTV-519 fumarate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JTV-5191883549-36-7K201JTV519JTV 519K 201K-201OthersSERCARyanodine receptorsInhibitorinhibitorinhibit

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JTV-519 fumarate
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HY-110312
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