2. MAPK/ERK Pathway
  3. p38 MAPK
  4. JX401

JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation.

For research use only. We do not sell to patients.

JX401 Chemical Structure

JX401 Chemical Structure

CAS No. : 349087-34-9

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Customer Review

Based on 1 publication(s) in Google Scholar

JX401 Related Antibodies

Top Publications Citing Use of Products

View All p38 MAPK Isoform Specific Products:

View All Isoforms
p38 MAPK p38α p38β MAPK13 p38δ p38γ

  • Biological Activity

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Description

JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation[1].

Molecular Weight

355.49

Formula

C21H25NO2S
CAS No.
SMILES

O=C(C1=CC=C(SC)C=C1OC)N2CCC(CC3=CC=CC=C3)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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JX401 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JX401349087-34-9JX 401JX-401p38 MAPKp38alpha4-benzylpiperidinehyperactiveinflammatory diseasesInhibitorinhibitorinhibit

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