2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. KCa2 channel modulator 1

KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype.

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KCa2 channel modulator 1 Chemical Structure

KCa2 channel modulator 1 Chemical Structure

CAS No. : 1019106-73-0

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Description

KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype[1].

Molecular Weight

331.78

Formula

C16H15ClFN5
CAS No.
SMILES

CC1=CC(NC2=CC=C(F)C(Cl)=C2)=NC(N3N=C(C)C=C3C)=N1
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KCa2 channel modulator 1 Related Classifications

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Keywords:

KCa2 channel modulator 11019106-73-0Potassium ChannelKcsAsubtypeselectivepositive modulatorchannelspinocerebellar ataxia type 2 (SCA2)ataxiaInhibitorinhibitorinhibit

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