Kdo Azide 

Kdo Azide is a click chemistry reagent containing an azide. Kdo Azide is a metabolic labeling reagent^[1]. Kdo Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension —Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.?

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

280.24

C₈H₁₆N₄O₇

1380099-68-2

Solid

White to light yellow

[N-]=[N+]=NC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CC(C(O)=O)=O.N

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Fugier E, et al. Rapid and Specific Enrichment of Culturable Gram Negative Bacteria Using Non-Lethal Copper-Free Click Chemistry Coupled with Magnetic Beads Separation. PLoS One. 2015 Jun 10;10(6):e0127700.  [Content Brief]