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  4. KF-14124

KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency.

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KF-14124 Chemical Structure

KF-14124 Chemical Structure

CAS No. : 134186-26-8

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KF-14124 Related Antibodies

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Description

KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency[1][2].

In Vivo

KF-14124 (0.3 mg/kg intraduodenal administration (i.d.)) tends to decrease left ventricular end-diastolic pressure (LVEDP) in a Propranolol-induced heart failure model (dogs) and shows a potent protective effect against reperfusion arrhythmia in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

409.50

Formula

C19H27N3O5S
CAS No.
SMILES

O=[N+]([O-])O[C@@H]1[C@](OC[C@@H]2N3CCN(CCCSC4=CC=CC=C4)CC3)([H])[C@]2([H])OC1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KF-14124 Related Classifications

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Keywords:

KF-14124134186-26-8KF14124KF 14124Othersvasodilatorcoronary vasospasmreperfusion arrhythmiaInhibitorinhibitorinhibit

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