2. Apoptosis
  3. TNF Receptor
  4. KF24345 free base

KF24345 free base is an orally active adenosine uptake inhibitor. KF24345 free base inhibits adenosine uptake by human, mouse, rabbit and hamster erythrocytes with IC50 values ??of 59.5, 130.1, 104.2 and 30.9 nM, respectively. KF24345 free base has anti-inflammatory activity and can inhibit LPS-induced TNF-α production and leukopenia in mice.

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KF24345 free base Chemical Structure

KF24345 free base Chemical Structure

CAS No. : 178750-21-5

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KF24345 free base Related Antibodies

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

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Description

KF24345 free base is an orally active adenosine uptake inhibitor. KF24345 free base inhibits adenosine uptake by human, mouse, rabbit and hamster erythrocytes with IC50 values ??of 59.5, 130.1, 104.2 and 30.9 nM, respectively. KF24345 free base has anti-inflammatory activity and can inhibit LPS-induced TNF-α production and leukopenia in mice[1].

Molecular Weight

574.67

Formula

C31H38N6O5
CAS No.
SMILES

O=C(N(C1=C(C2=O)C=C(C=C1)C)C)N2C3CCN(CC3)C4=C5C=C(C(OCC)=CC5=NC(N6CCOCC6)=N4)OCC
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KF24345 free base Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KF24345178750-21-5KF 24345KF-24345TNF ReceptorTumor Necrosis Factor ReceptorTNFROrally activeadenosine uptakeinhibitorerythrocyteanti-inflammatoryInhibitorinhibit

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