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  3. KOdiA-PC

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

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KOdiA-PC Chemical Structure

KOdiA-PC Chemical Structure

CAS No. : 439904-33-3

Size Price Stock Quantity
Solvent
500μg (7.53 mM * 100 μL in Ethanol) USD 110 In-stock
Solvent
1mg (7.53 mM * 200 μL in Ethanol) USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

Molecular Weight

663.78

Formula

C32H58NO11P

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCC(/C=C/C(O)=O)=O)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: ≥99.0%

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KOdiA-PC
Cat. No.:
HY-126726
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