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  4. KP 544

KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective.

For research use only. We do not sell to patients.

KP 544 Chemical Structure

KP 544 Chemical Structure

CAS No. : 393856-87-6

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KP 544 Related Antibodies

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Description

KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective[1].

Molecular Weight

342.82

Formula

C18H19ClN4O
CAS No.
SMILES

O[C@H]1CC[C@H](NC2=NC(N)=NC=C2C#CC3=CC=C(Cl)C=C3)CC1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KP 544 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KP 544393856-87-6KP544KP-544Othersneurotrophic protein enhancerNGFPC12 cellsSH-SY5Y neuroblastoma cellscholine acetyltransferaseneuroprotectiveInhibitorinhibitorinhibit

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