KQFK TFA

Cat. No.: HY-P3970D Purity: 99.12%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

KQFK TFA is the TFA salt form of KQFK (HY-P3970C). KQFK TFA is an inactive control of KRFK (HY-P3970). KRFK is a peptide derived from TSP-1 that can activate TGF-β.

For research use only. We do not sell to patients.

KQFK TFA Chemical Structure

Size	Price	Stock
5 mg	USD 50	Ask For Quote & Lead Time
10 mg	USD 72	Ask For Quote & Lead Time
25 mg	USD 145	Ask For Quote & Lead Time
50 mg	USD 230	Ask For Quote & Lead Time

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of KQFK TFA:

KRFK Get quote
KQFK Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

KQFK TFA is the TFA salt form of KQFK (HY-P3970C). KQFK TFA is an inactive control of KRFK (HY-P3970). KRFK is a peptide derived from TSP-1 that can activate TGF-β^[1].

Molecular Weight

891.73

Formula

C₃₂H₄₆F₉N₇O₁₂

Appearance

Solid

Color

White to off-white

Sequence

Lys-Gln-Phe-Lys

Sequence Shortening

KQFK

SMILES

O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CCCCN)N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (112.14 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1214 mL	5.6071 mL	11.2142 mL
5 mM	0.2243 mL	1.1214 mL	2.2428 mL
10 mM	0.1121 mL	0.5607 mL	1.1214 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.12%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (248 KB) RP-HPLC (258 KB) MS (82 KB)

Handling Instructions (2659 KB)

References

[1]. Murphy-Ullrich JE, et al. Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology. Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):59-69. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.1214 mL	5.6071 mL	11.2142 mL	28.0354 mL
	5 mM	0.2243 mL	1.1214 mL	2.2428 mL	5.6071 mL
	10 mM	0.1121 mL	0.5607 mL	1.1214 mL	2.8035 mL
	15 mM	0.0748 mL	0.3738 mL	0.7476 mL	1.8690 mL
	20 mM	0.0561 mL	0.2804 mL	0.5607 mL	1.4018 mL
	25 mM	0.0449 mL	0.2243 mL	0.4486 mL	1.1214 mL
	30 mM	0.0374 mL	0.1869 mL	0.3738 mL	0.9345 mL
	40 mM	0.0280 mL	0.1402 mL	0.2804 mL	0.7009 mL
	50 mM	0.0224 mL	0.1121 mL	0.2243 mL	0.5607 mL
	60 mM	0.0187 mL	0.0935 mL	0.1869 mL	0.4673 mL
	80 mM	0.0140 mL	0.0701 mL	0.1402 mL	0.3504 mL
	100 mM	0.0112 mL	0.0561 mL	0.1121 mL	0.2804 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

KQFK TFA Related Classifications

Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KQFKTGF-β ReceptorTransforming growth factor beta receptorsInhibitorinhibitorinhibit

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