2. Anti-infection
  3. Bacterial
  4. KR-12 (human)

KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

KR-12 (human) Chemical Structure

KR-12 (human) Chemical Structure

CAS No. : 1218951-51-9

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1 mg USD 70 In-stock
5 mg USD 175 In-stock
10 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

KR-12 (human) Related Antibodies

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Description

KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM[1].

Molecular Weight

1570.93

Formula

C71H127N25O15
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
Sequence Shortening

KRIVQRIKDFLR-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (63.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6366 mL 3.1828 mL 6.3657 mL
5 mM 0.1273 mL 0.6366 mL 1.2731 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6366 mL 3.1828 mL 6.3657 mL 15.9141 mL
5 mM 0.1273 mL 0.6366 mL 1.2731 mL 3.1828 mL
10 mM 0.0637 mL 0.3183 mL 0.6366 mL 1.5914 mL
15 mM 0.0424 mL 0.2122 mL 0.4244 mL 1.0609 mL
20 mM 0.0318 mL 0.1591 mL 0.3183 mL 0.7957 mL
25 mM 0.0255 mL 0.1273 mL 0.2546 mL 0.6366 mL
30 mM 0.0212 mL 0.1061 mL 0.2122 mL 0.5305 mL
40 mM 0.0159 mL 0.0796 mL 0.1591 mL 0.3979 mL
50 mM 0.0127 mL 0.0637 mL 0.1273 mL 0.3183 mL
60 mM 0.0106 mL 0.0530 mL 0.1061 mL 0.2652 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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KR-12 (human) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KR-12 (human)1218951-51-9BacterialE. coliLL-37Inhibitorinhibitorinhibit

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