2. PI3K/Akt/mTOR
  3. PI4K
  4. KR-27370

KR-27370 (compound 7f) is an antiviral agent and selective PI4KIIIβ/PI4KIIIα inhibitor (IC50: 3.1 nM/15.8 nM), against hRV, Ke Saatchivirus and other enteroviruses have inhibitory activity[1].br/.

For research use only. We do not sell to patients.

KR-27370 Chemical Structure

KR-27370 Chemical Structure

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KR-27370 Related Antibodies

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PI4KIIIβ PI4KIIIα PI4K PI4KII

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Description

KR-27370 (compound 7f) is an antiviral agent and selective PI4KIIIβ/PI4KIIIα inhibitor (IC50: 3.1 nM/15.8 nM), against hRV, Ke Saatchivirus and other enteroviruses have inhibitory activity[1].br/[1].

IC50 & Target

PI4KIIIβ

3.1 nM (IC50, [1])

PI4KIIIα

15.8 nM (IC50, [1])

In Vitro

KR-27370 has low cytotoxicity (CC50: >100 μM, H1HeLa), and its EC50 against hRV B14, hRV A16, and hRV A21 are 22 nM, 32 nM, and 36 nM respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

KR-27370 Related Antibodies
Molecular Weight

553.65

Formula

C27H27N3O6S2
SMILES

COC1=CC(OC)=CC(CC(NC2=NC(C)=C(C3=CC=C(OC)C(NS(C4=CC=CC=C4)(=O)=O)=C3)S2)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KR-27370 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KR-27370KR27370KR 27370PI4KPhosphatidylinositol 4 kinasesPI4 kinaseshRVcoxsackievirusenterovirusInhibitorinhibitorinhibit

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KR-27370
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HY-161357
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