2. PROTAC GPCR/G Protein MAPK/ERK Pathway
  3. PROTACs Ras
  4. KRAS degrader-1

KRAS degrader-1 (compound 1) is a potent KRAS degrader. KRAS degrader-1 target specific proteins for degradation through the autophagy-lysosomal degradation pathway.

For research use only. We do not sell to patients.

KRAS degrader-1 Chemical Structure

KRAS degrader-1 Chemical Structure

CAS No. : 2795275-59-9

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KRAS degrader-1 Related Antibodies

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Description

KRAS degrader-1 (compound 1) is a potent KRAS degrader. KRAS degrader-1 target specific proteins for degradation through the autophagy-lysosomal degradation pathway[1].

Molecular Weight

1283.25

Formula

C55H57Br2ClFIN8O7
CAS No.
SMILES

BrC(C=C(C=C1Br)/C=C2C3=CC(I)=CC=C3NC/2=O)=C1OCCOCCOCCOCCCN(CCC4)[C@@H]4COC5=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C7C(CN(C8=CC=CC9=C8C(Cl)=CC=C9)CC7)=N5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS degrader-1 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS degrader-12795275-59-9KRAS degrader1KRAS degrader 1PROTACsRasInhibitorinhibitorinhibit

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