1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. KRAS G12C inhibitor 68

KRAS G12C inhibitor 68 (compound I-063) is a KRAS G12C inhibitor with an IC50 of 7 nM. KRAS G12C inhibitor 68 has anti-tumor activity.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 68 Chemical Structure

KRAS G12C inhibitor 68 Chemical Structure

CAS No. : 3034851-27-6

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Description

KRAS G12C inhibitor 68 (compound I-063) is a KRAS G12C inhibitor with an IC50 of 7 nM. KRAS G12C inhibitor 68 has anti-tumor activity[1].

IC50 & Target

KRas G12C

7 nM (IC50)

Molecular Weight

634.76

Formula

C35H44F2N6O3

CAS No.
SMILES

FC(C1=C2C(N3[C@](CC=C2)([H])[C@H](N4CCN(CC4)C(C=C)=O)C3)=CC(N5[C@@H](C[C@@H](C6=C(C7(COC7)OC)N=CC=C6C)CC5)C)=N1)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
KRAS G12C inhibitor 68
Cat. No.:
HY-159611
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