2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRAS inhibitor-8

KRAS inhibitor-8 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound C.

For research use only. We do not sell to patients.

KRAS inhibitor-8 Chemical Structure

KRAS inhibitor-8 Chemical Structure

CAS No. : 2022986-70-3

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KRAS inhibitor-8 Related Antibodies

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Description

KRAS inhibitor-8 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound C[1].

IC50 & Target[1]

KRAS(G12C)

 

Molecular Weight

565.95

Formula

C26H24ClF4N5O3
CAS No.
SMILES

C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(F)C=CC=C4O)=C(F)C3=NC(OCCN5CC(F)(F)C5)=N2)CC1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS inhibitor-8 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS inhibitor-82022986-70-3KRAS inhibitor8KRAS inhibitor 8RasmutantKRAScancerGTPphosphateactiveGDPconformationInhibitorinhibitorinhibit

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