2. GPCR/G Protein MAPK/ERK Pathway
  3. Ras
  4. KRASG12C IN-12

KRASG12C IN-12 (compound-1) is a KRASG12C inhibitor. KRASG12C IN-12 (compound-1) can form a ternary complex with intracellular CYPA and the activated KRASG12C mutant.

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KRASG12C IN-12 Chemical Structure

KRASG12C IN-12 Chemical Structure

CAS No. : 2093328-45-9

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KRASG12C IN-12 Related Antibodies

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Description

KRASG12C IN-12 (compound-1) is a KRASG12C inhibitor. KRASG12C IN-12 (compound-1) can form a ternary complex with intracellular CYPA and the activated KRASG12C mutant[1].

IC50 & Target[1]

KRas G12C

 

Molecular Weight

617.78

Formula

C29H39N5O6S2
CAS No.
SMILES

O=C(N1N[C@@H](CCC1)C(OC)=O)[C@@H](NC([C@H](C(C)C)NC(CCCSSC2=CC=CC=N2)=O)=O)CC3=CC(O)=CC=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRASG12C IN-12 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRASG12C IN-122093328-45-9RasInhibitorinhibitorinhibit

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