2. Immunology/Inflammation
  3. Interleukin Related
  4. KRN7000 analog 3

KRN7000 analog 3 (Compound 14),α-GalCer (HY-102022) analogue with 4-phenoxy substitution, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (range: 49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1.2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants.

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KRN7000 analog 3 Chemical Structure

KRN7000 analog 3 Chemical Structure

CAS No. : 1384423-78-2

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KRN7000 analog 3 Related Antibodies

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Description

KRN7000 analog 3 (Compound 14),α-GalCer (HY-102022) analogue with 4-phenoxy substitution, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (range: 49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1.2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants[1].

Molecular Weight

816.11

Formula

C47H77NO10
CAS No.
SMILES

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](NC(CCCCCCCCCCC1=CC=C(C=C1)OC2=CC=CC=C2)=O)CO[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO
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Purity & Documentation
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KRN7000 analog 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRN7000 analog 31384423-78-2Interleukin RelatedILα-GalCer analogueIL-2 cytokineInhibitorinhibitorinhibit

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