2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. KT-531

KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers.

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KT-531 Chemical Structure

KT-531 Chemical Structure

CAS No. : 2490284-18-7

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KT-531 Related Antibodies

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HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

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Description

KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers[1].

Molecular Weight

418.36

Formula

C17H14F4N2O4S
CAS No.
SMILES

O=C(NO)C1=CC=C(CN(C2CC2)S(=O)(C3=CC(F)=C(F)C(F)=C3F)=O)C=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KT-531 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KT-5312490284-18-7KT531KT 531HDACHistone deacetylasesHDAC6 InhibitorT?Cell Prolymphocytic LeukemiaSUP-T11Hematological cancerInhibitorinhibitorinhibit

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