2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. KWWCRW

KWWCRW is a Holliday linker inhibitory peptide with anticancer activity. KWWCRW inhibits homologous recombination repair (HDR) during DNA repair by binding to the reactive Holliday linker intermediate and preventing its degradation, and inhibits site-specific recombination by bacteriophage in vitro.

For research use only. We do not sell to patients.

KWWCRW Chemical Structure

KWWCRW Chemical Structure

CAS No. : 292148-25-5

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KWWCRW Related Antibodies

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Description

KWWCRW is a Holliday linker inhibitory peptide with anticancer activity. KWWCRW inhibits homologous recombination repair (HDR) during DNA repair by binding to the reactive Holliday linker intermediate and preventing its degradation, and inhibits site-specific recombination by bacteriophage in vitro[1].

Molecular Weight

964.15

Formula

C48H61N13O7S
CAS No.
Sequence

Lys-Trp-Trp-Cys-Arg-Trp
Sequence Shortening

KWWCRW
SMILES

NCCCC[C@H](N)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@H](C(N[C@@H](CS)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KWWCRW Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KWWCRW292148-25-5DNA/RNA SynthesisHoliday connectoranticancerhomologous recombinationinhibitorDNA repairInhibitorinhibit

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