1. Metabolic Enzyme/Protease
  2. Acyltransferase
  3. KY-455

KY-455 is a novel inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). KY-455 inhibita rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC50 values of 0.4, 0.9, 2.9 and 4.1 μmol/L, respectively.

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KY-455 Chemical Structure

KY-455 Chemical Structure

CAS No. : 178469-71-1

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Description

KY-455 is a novel inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT). KY-455 inhibita rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC50 values of 0.4, 0.9, 2.9 and 4.1 μmol/L, respectively.

Molecular Weight

316.48

Formula

C20H32N2O

CAS No.
SMILES

O=C(C(C)(C)C)NC1=C(C)C=C(C)C2=C1N(CCCCC)CC2

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KY-455
Cat. No.:
HY-167664
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