2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. COX Lipoxygenase
  4. L-651896

L-651896 is a compound with anti-inflammatory and antiproliferative activities that inhibits 5-lipoxygenase and cyclooxygenase, thereby reducing the production of leukotrienes and prostaglandins. L-651896 can be used in the study of skin diseases and other inflammatory diseases.

For research use only. We do not sell to patients.

L-651896 Chemical Structure

L-651896 Chemical Structure

CAS No. : 99134-29-9

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L-651896 Related Antibodies

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Description

L-651896 is a compound with anti-inflammatory and antiproliferative activities that inhibits 5-lipoxygenase and cyclooxygenase, thereby reducing the production of leukotrienes and prostaglandins. L-651896 can be used in the study of skin diseases and other inflammatory diseases[1].

Cellular Effect
Cell Line Type Value Description References
RBL-1 IC50
0.25 μM
Compound: L-651896
Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell line
Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell line
[PMID: 2104936]
Molecular Weight

282.33

Formula

C18H18O3
CAS No.
SMILES

OCC1=C(/C=C/CC2=C(O)C=C(CCO3)C3=C2)C=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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L-651896 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-65189699134-29-9L651896L 651896COXLipoxygenaseCyclooxygenaseLOXAnti-inflammatory activityantiproliferative activityprostaglandinsleukotriene5-lipoxygenaseInhibitorinhibitorinhibit

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