1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. L-659837

L-659837 is a NK2 receptor antagonist, and can antagonize GR 64349 (HY-P1278)-induced contraction. L-659837 can be used for study of urinary bladder disorders.

For research use only. We do not sell to patients.

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L-659837 Chemical Structure

L-659837 Chemical Structure

CAS No. : 125989-10-8

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Description

L-659837 is a NK2 receptor antagonist, and can antagonize GR 64349 (HY-P1278)-induced contraction. L-659837 can be used for study of urinary bladder disorders[1].

Molecular Weight

788.96

Formula

C40H52N8O7S

CAS No.
Sequence

Cyclo(Gln-Trp-Phe-{(R)Gly(ANC-2)}-Leu-Met)

Sequence Shortening

Cyclo(QWF-{(R)Gly(ANC-2)}-LM)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
L-659837
Cat. No.:
HY-P2436
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