1. Metabolic Enzyme/Protease
  2. HMG-CoA Reductase (HMGCR)
  3. L-669,262

L-669,262  (Synonyms: 6-Oxo Simvastatin; Iso-simvastatin-6-one)

Cat. No.: HY-117581
Handling Instructions

L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA.

For research use only. We do not sell to patients.

L-669,262 Chemical Structure

L-669,262 Chemical Structure

CAS No. : 130468-11-0

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Description

L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA[1].

Molecular Weight

432.55

Formula

C25H36O6

CAS No.
SMILES

CCC(C)(C(O[C@H]1CC(C)=CC2=CC([C@@H]([C@@H]([C@@]12[H])CC[C@@H]3C[C@H](CC(O3)=O)O)C)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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