2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. L 775,606

L 775,606 is a potent and selective 5-HT1D receptor agonist. L 775,606 can be used to study migraine headache.

For research use only. We do not sell to patients.

L 775,606 Chemical Structure

L 775,606 Chemical Structure

CAS No. : 188400-51-3

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L 775,606 Related Antibodies

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Description

L 775,606 is a potent and selective 5-HT1D receptor agonist. L 775,606 can be used to study migraine headache[1].

Cellular Effect
Cell Line Type Value Description References
CHO-K1 IC50
0.6 nM
Compound: L-775606
Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation counting
Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation counting
[PMID: 18507369]
Molecular Weight

432.54

Formula

C25H29FN6
CAS No.
SMILES

FC1=CC(CCN2CCN(CC2)CCCC3=CNC4=C3C=C(C=C4)N5C=NN=C5)=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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L 775,606 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L 775,606188400-51-35-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorhepatic metabolism5-HT receptormigraine headacheInhibitorinhibitorinhibit

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