L-Alanine-d₃ (Synonyms: L-2-Aminopropionic acid-d₃)

Cat. No.: HY-N0229S12 Purity: 99.96%: FAQs
Data Sheet SDS COA Handling Instructions

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L-Alanine-d₃ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

For research use only. We do not sell to patients.

L-Alanine-d<sub>3</sub> Chemical Structure

L-Alanine-d₃ Chemical Structure

CAS No. : 63546-27-0

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
25 mg	USD 40	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 68	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 114	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 233	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
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5 g		Get quote

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Other Forms of L-Alanine-d₃:

L-Alanine In-stock

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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

92.11

Formula

C₃H₄D₃NO₂

CAS No.

63546-27-0

Unlabeled CAS

56-41-7

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)C([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 66.67 mg/mL (723.81 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	10.8566 mL	54.2829 mL	108.5658 mL
5 mM	2.1713 mL	10.8566 mL	21.7132 mL
10 mM	1.0857 mL	5.4283 mL	10.8566 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.96%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (250 KB) HNMR (697 KB) RP-HPLC (834 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	10.8566 mL	54.2829 mL	108.5658 mL	271.4146 mL
	5 mM	2.1713 mL	10.8566 mL	21.7132 mL	54.2829 mL
	10 mM	1.0857 mL	5.4283 mL	10.8566 mL	27.1415 mL
	15 mM	0.7238 mL	3.6189 mL	7.2377 mL	18.0943 mL
	20 mM	0.5428 mL	2.7141 mL	5.4283 mL	13.5707 mL
	25 mM	0.4343 mL	2.1713 mL	4.3426 mL	10.8566 mL
	30 mM	0.3619 mL	1.8094 mL	3.6189 mL	9.0472 mL
	40 mM	0.2714 mL	1.3571 mL	2.7141 mL	6.7854 mL
	50 mM	0.2171 mL	1.0857 mL	2.1713 mL	5.4283 mL
	60 mM	0.1809 mL	0.9047 mL	1.8094 mL	4.5236 mL
	80 mM	0.1357 mL	0.6785 mL	1.3571 mL	3.3927 mL
	100 mM	0.1086 mL	0.5428 mL	1.0857 mL	2.7141 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

L-Alanine-d₃ Related Classifications

Neurological Disease Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Alanine-d₃63546-27-0L-2-Aminopropionic acid-d₃Endogenous MetaboliteInhibitorinhibitorinhibit

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L-Alanine-d3 (Synonyms: L-2-Aminopropionic acid-d3)

Other Forms of L-Alanine-d3:

L-Alanine-d3 Related Antibodies

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Complete Stock Solution Preparation Table

L-Alanine-d3 Related Classifications