2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. NO Synthase Endogenous Metabolite
  4. L-Arginine-13C6,15N4 hydrochloride

L-Arginine-13C6,15N4 hydrochloride  (Synonyms: (S)-(+)-Arginine-13C6,15N4 hydrochloride)

Cat. No.: HY-N0455AS8 Purity: ≥99.0%
COA Handling Instructions

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L-Arginine-13C6,15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

For research use only. We do not sell to patients.

L-Arginine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub> hydrochloride Chemical Structure

L-Arginine-13C6,15N4 hydrochloride Chemical Structure

CAS No. : 202468-25-5

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1 mg USD 55 In-stock
5 mg USD 150 In-stock
10 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of L-Arginine-13C6,15N4 hydrochloride:

L-Arginine-13C6,15N4 hydrochloride Related Antibodies

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Description

L-Arginine-13C6,15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Arginine-13C6,15N4 hydrochloride Related Antibodies
Molecular Weight

220.59

Formula

13C6H15Cl15N4O2
CAS No.
Unlabeled CAS

1119-34-2
Appearance

Solid

Color

White to off-white

SMILES

[15NH]=[13C]([15NH2])[15NH][13CH2][13CH2][13CH2][13C@H]([15NH2])[13C](O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (566.66 mM; Need ultrasonic)

H2O : 125 mg/mL (566.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5333 mL 22.6665 mL 45.3330 mL
5 mM 0.9067 mL 4.5333 mL 9.0666 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 4.5333 mL 22.6665 mL 45.3330 mL 113.3324 mL
5 mM 0.9067 mL 4.5333 mL 9.0666 mL 22.6665 mL
10 mM 0.4533 mL 2.2666 mL 4.5333 mL 11.3332 mL
15 mM 0.3022 mL 1.5111 mL 3.0222 mL 7.5555 mL
20 mM 0.2267 mL 1.1333 mL 2.2666 mL 5.6666 mL
25 mM 0.1813 mL 0.9067 mL 1.8133 mL 4.5333 mL
30 mM 0.1511 mL 0.7555 mL 1.5111 mL 3.7777 mL
40 mM 0.1133 mL 0.5667 mL 1.1333 mL 2.8333 mL
50 mM 0.0907 mL 0.4533 mL 0.9067 mL 2.2666 mL
60 mM 0.0756 mL 0.3778 mL 0.7555 mL 1.8889 mL
80 mM 0.0567 mL 0.2833 mL 0.5667 mL 1.4167 mL
100 mM 0.0453 mL 0.2267 mL 0.4533 mL 1.1333 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Arginine-13C6,15N4 hydrochloride Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Arginine-13C6,15N4202468-25-5(S)-(+)-Arginine-13C6,15N4NO SynthaseEndogenous MetaboliteNitric oxide synthasesNOSInhibitorinhibitorinhibit

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